The Emerging Role of Fatty Acid Synthase in Hypoxia-Induced Pulmonary Hypertensive Mouse Energy Metabolism

Figure 5

Effect of C75 and FAS shRNA treatment on HPASMCs. (a) Quantification of FFA (palmitate) levels in HPASMCs (). (b, c) Quantification of FAS activity and malonyl CoA levels in the HPASMCs (). (d–i) Quantification of mRNA levels of CASPASE 3, CASPASE 9, and HIF1 upon C75 or shFAS treatment in the HPASMCs ().

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