TMIGD1 Inhibited Abdominal Adhesion Formation by Alleviating Oxidative Stress in the Mitochondria of Peritoneal Mesothelial Cells

Figure 2

TMIGD1 expression is decreased in mesothelial cells. (a) IHC showing TMIGD1 expression in adhesion tissue and normal peritoneum of a mouse abdominal adhesion model at POD 3 and 10. ; the black arrows mark the normal peritoneum or adhesion tissue; 400x magnification. (b) Score of TMIGD1 in the pictures of IHC of adhesion tissue and normal peritoneum of the mouse abdominal adhesion model at POD 3 and 10. ; compared to normal tissue, ; test. (c) Quantitation of qPCR for TMIGD1 shows downregulation of expression in mouse adhesion tissue (compared to the normal peritoneum of each time point) at POD 3 and 10. ; compared to normal tissue, ; compared to normal tissue, ; test. (d) IHF for TMIGD1 (green) and CK19 (red) in mouse adhesion tissue at POD 3 and 10. ; the yellow brackets show normal peritoneum or adhesion tissue; 900x magnification. (e) Quantification of corresponding fluorescence intensities for TMIGD1 in mesothelial cells of IHF. ; compared to normal tissue, ; test.

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