Inositol Alleviates Pulmonary Fibrosis by Promoting Autophagy via Inhibiting the HIF-1α-SLUG Axis in Acute Respiratory Distress Syndrome

Figure 2

Inositol attenuated the release of cytokines from ARDS model cells by activating autophagy. (a) The levels of IL-1β, IL-6, IL-17, and MCP-1 in LPS-induced HPAEpiCs with and without inositol treatment were detected by ELISA. (b) LC3B immunofluorescence staining was performed to detect autophagy changes in LPS-induced HPAEpiCs with and without inositol treatment, . (c) Autophagosome changes in HPAEpiCs from the different groups as detected by TEM, . Data represent the mean , , Model vs. Blank: ; ^#, Model with Inositol vs. Model: ^##, ^###.

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