[Retracted] Expression Profile of Inflammation Response Genes and Potential Regulatory Mechanisms in Dilated Cardiomyopathy

Figure 4

The cell activity scores of cell clusters. (a) The score of the IRG set. The threshold was 0.26, and the active scores of 7176 cells exceeded the threshold. (b) The UMAP dimensional plot according to the active score of each cell cluster. (c–f) GO and KEGG pathway enrichment analyses of DEGs in high and low active cell clusters. GSEA for pathways in KEGG includes systemic lupus erythematosus, cytokine–cytokine receptor interaction, primary immunodeficiency, and ribosome. GSEA for molecular function in GO includes MHC class II receptor activity, immunoglobulin binding, IGG binding, immunoglobulin receptor binding, and signaling adaptor activity. GSEA for biological process in GO includes T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting, B cell homeostasis, and endogenous peptide antigen via MHC class I tap independent. GSEA for cellular component in GO includes MHC class II protein complex, large ribosomal subunit, MHC class I protein complex, immunoglobulin complex, and immunoglobulin complex circulating.

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