∆nFGF1 Protects β-Cells against High Glucose-Induced Apoptosis via the AMPK/SIRT1/PGC-1α Axis

Figure 1

The glucose-lowering effect of ∆nFGF1 in db/db mice. (a) The 10-week-old db/db mice received every other day intraperitoneal injection of ∆nFGF1 (0.5 mg/kg) or saline for eight weeks, with age-matched nondiabetic db/m littermates served as the normal control group. (b, c) Random nonfasted blood glucose and changes, (d, e) average food intake and water intake per mouse, and (f, g) body weight alteration. All data are presented as . mice per group. , , and . n.s.: no significance.

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