Characterization of Acetylation of Histone H3 at Lysine 9 in the Trigeminal Ganglion of a Rat Trigeminal Neuralgia Model

Figure 5

Overview of HDAC3 in TN rat model. (a) Overall calling peaks of HDAC3 in the rat genome of the control, TN rat model, and TN rat model administered CBZ treatment, by ChIP-seq. (b) Metagene profiles of genome-wide HDAC3 in the control, TN rat model, and TN rat model administered CBZ treatment. (c) Diagram showing intersecting genes with differential HDAC3 enrichment in the control, TN rat model, and TN rat model administered CBZ treatment. (d) Correlation analysis of DEGs with differential H3K9ac and HDAC3 enrichment in the control, TN rat model, and TN rat model administered CBZ treatment. (e) Gene-browser views of transcriptome, H3K9ac, and HDAC3 profiles of Neurod2, C2cd4c, and Sf3b4 in the control, TN rat model, and TN rat model administered CBZ treatment.

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