Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury

Figure 4

Maltol attenuated H₂O₂-induced oxidative stress and apoptosis in PC12 cells. (a–c) Adopting CCK-8 to measure relative cell viability after being treated with maltol, resveratrol, and α-vitamin E in different concentrations. per group. , , vs. H₂O₂ group. (d–e) Adopting the Calcein-AM/PI Double Stain Kit to distinguish live cells (green) from dead cells (red) and calculate cell viability. . (f–h) Western blots analysis of HO-1 and SOD2 in vitro experiments. per group. Values were given as . , , , and NS (not significant).

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