Downregulation of Inflammatory Response via Nrf2/Trx1/TXNIP Axis in Oxidative Stress-Induced ARPE-19 Cells and Mouse Model of AMD

<div>Effect of Nrf2 and Trx1 on cell migration. (a) A scratch test on ARPE-19 cells. The images were recorded at 0, 24, and 48 h. Magnification: ×500, scale bar: 50 <i>μ</i>m. (b) Quantitative analysis of the changes in cell migration at 24 and 48 h. (c) Transwell experiment after the treatment of ARPE-19 cells. (d) Quantitative analysis of invasion ability. Scale bar: 50 <i>μ</i>m. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Downregulation of Inflammatory Response via Nrf2/Trx1/TXNIP Axis in Oxidative Stress-Induced ARPE-19 Cells and Mouse Model of AMD 