Endogenous Vasoactive Peptides and Vascular Aging-Related Diseases

Figure 7

The vascular roles of CNP. CNP inhibits vascular inflammation and promotes vascular remodeling and vasodilation via its receptors NPR-B or NPR-C. Abbreviations: Akt: protein kinase B; cGMP; cyclic guanosine monophosphate; CNP: C-type natriuretic peptide; ERK: extracellular regulated protein kinases; NPR: natriuretic peptide receptor; PI3K: phosphatidylinositol 3 kinase.