MDL-800, the SIRT6 Activator, Suppresses Inflammation via the NF-κB Pathway and Promotes Angiogenesis to Accelerate Cutaneous Wound Healing in Mice

Figure 7

The capacity of promoting collagen deposition of MDL-800 in vivo. (a) Representative Masson’s trichrome-stained sections of dorsal skin wound samples from different groups on day 9 and day 18. (b) Immunostaining for type I collagen and type Ill collagen of the control, 5 mg/kg, and 25 mg/kg groups on day 9. . (c) Quantification analysis of relative collagen density corresponding to Masson’s trichrome staining of the groups mentioned above on day 9 and day 18. per group. (d, e) Quantification analysis of relative density of type I collagen and type Ill collagen of the groups mentioned above on day 9. per group ().

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