Arterial Pulsatility Augments Microcirculatory Perfusion and Maintains the Endothelial Integrity during Extracorporeal Membrane Oxygenation via hsa_circ_0007367 Upregulation in a Canine Model with Cardiac Arrest

Figure 2

Pulsatility attenuates lung injury and upregulates the expression of hsa_circ_0007367 (circUBAP2), which is a microcirculation-related circRNA. (a) Representative images of lung tissues with hematoxylin and eosin staining in nonpulsatile group animals after 6 hours of ECMO; (b) representative images of lung tissues with hematoxylin and eosin staining in pulsatile group animals after 6 hours of ECMO; (c) comparison of the circUBAP2 expressions in lung tissues between these two groups; (d) correlation analysis between the expression of circUBAP2 and the PVD value; (e) correlation analysis between the expression of circUBAP2 and the MFI value. Significantly different between groups, . Abbreviations: PVD: perfused vessel density; MFI: microvascular flow index.

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