DRDB: A Machine Learning Platform to Predict Chemical-Protein Interactions towards Diabetic Retinopathy

Figure 5

Target validation in ARPE19 cells. Ctrl: control group; HG: high glucose group. (a) The effect of CDDP on the relative viability of ARPE19 cells. (b) The effect of CDDP on the expression of ICAM-1 in the presence of high glucose. (c) The effect of protocatechuic acid on the expression of ICAM-1 in the presence of high glucose. (d) The effect of cryptotanshinone on the expression of ICAM-1 in the presence of high glucose.

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