Research Article

Mesangial Cell–Derived Exosomal miR-4455 Induces Podocyte Injury in IgA Nephropathy by Targeting ULK2

Figure 5

Effect of mesangial cell exosomes combined with ULK2 overexpression plasmid transfection on podocytes activity and apoptosis. (a) Effect of MC-ExoC or MC-ExoI combined with ULK2 overexpression plasmid transfection on the ULK2 expression in human podocytes revealed by western blotting. (b) Effect of MC-ExoC or MC-ExoI combined with ULK2 overexpression plasmid transfection on human podocytes activity by CCK8. (c) Effect of MC-ExoC or MC-ExoI combined with ULK2 overexpression plasmid transfection on apoptosis of human podocytes by flow cytometry (, ns means ).
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