Significance of TP53 Mutational Status-Associated Signature in the Progression and Prognosis of Endometrial Carcinoma

Figure 2

Construction of the TP53 mutational status-associated signature. (a) Heat map showing the top 40 DEGs between patients with TP53 mutation or not. (b) Volcano plot showing the DEGs between patients with TP53 mutation or not. (c) Regression coefficient of 17 DEGs based on the LASSO model. (d) Variables were screened by 10-fold cross-validation method in the LASSO model. When the number of DEG variables was 17, the value corresponding to the minimum partial likelihood deviation was obtained.

(a)

(b)

(c)

(d)