Significance of <i>TP53</i> Mutational Status-Associated Signature in the Progression and Prognosis of Endometrial Carcinoma

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr class="thead"><td class="align_left">id</td><td class="align_center">coef</td><td class="align_center">HR</td><td class="align_center">HR.95L</td><td class="align_center">HR.95H</td><td class="align_center"><svg height="10.2124pt" id="M21" style="vertical-align:-3.42943pt" version="1.1" viewbox="-0.0498162 -6.78297 7.83752 10.2124" width="7.83752pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M570 304C570 398 525 448 414 448C385 448 343 445 312 434L329 511L321 518C297 504 262 482 244 460L233 411C195 397 159 381 128 358L135 332C160 347 189 360 224 373L111 -147C97 -210 84 -218 17 -231L13 -257L254 -247L259 -218L233 -216C183 -212 177 -202 189 -142L218 -1C238 -10 266 -12 283 -12C351 3 429 48 483 105C543 168 570 242 570 304ZM482 289C482 161 380 33 304 33C278 33 248 51 233 69L303 396C326 400 352 403 369 403C428 403 482 380 482 289Z"></path></g></svg> value</td></tr><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr><td class="align_left">ERBB2</td><td class="align_center">0.001239</td><td class="align_center">1.001239</td><td class="align_center">1.000481</td><td class="align_center">1.001998</td><td class="align_center">0.00135</td></tr><tr><td class="align_left">GLOD5</td><td class="align_center">0.112093</td><td class="align_center">1.118617</td><td class="align_center">1.058151</td><td class="align_center">1.182539</td><td class="align_center"><span style="width: 55.9003ptpx;"><svg height="8.98583pt" id="M22" style="vertical-align:-0.3499308pt" version="1.1" viewbox="-0.0498162 -8.6359 55.9003 8.98583" width="55.9003pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M447 623H65C61 580 56 530 47 475H76C100 541 106 550 172 550H388C308 376 196 170 91 -1L98 -12L172 -2C268 204 360 408 455 611L447 623Z"></path></g><g transform="matrix(.013,0,0,-0.013,6.242,0)"><path d="M113 -12C146 -12 170 11 170 46C170 78 146 103 114 103S58 78 58 46C58 11 82 -12 113 -12Z"></path></g><g transform="matrix(.013,0,0,-0.013,9.206,0)"><path d="M447 623H65C61 580 56 530 47 475H76C100 541 106 550 172 550H388C308 376 196 170 91 -1L98 -12L172 -2C268 204 360 408 455 611L447 623Z"></path></g><g transform="matrix(.013,0,0,-0.013,15.448,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,21.688,0)"><path d="M593 650H142L136 622C219 616 224 611 209 531L130 120C114 39 108 34 23 28L17 0H501C518 32 557 130 568 158L540 169C519 132 495 93 469 70C439 43 409 35 332 35C272 35 241 37 225 50C211 61 211 89 222 149L253 320H350C441 320 443 312 441 239H471L510 434H481C455 366 448 358 360 358H260L303 572C311 613 312 615 348 615H431C509 615 522 603 532 581C544 555 546 531 545 491L574 493C583 555 592 631 593 650Z"></path></g><g transform="matrix(.013,0,0,-0.013,32.602,0)"><path d="M535 230V280H52V230H535Z"></path></g><g transform="matrix(.013,0,0,-0.013,43.139,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,49.379,0)"><path d="M153 550H386L412 615L406 623H120L82 318C104 327 142 338 184 338C294 338 347 275 347 187C347 112 305 39 221 39C160 39 119 71 97 89C88 97 80 96 71 90C59 80 50 67 49 57C48 45 52 36 66 23C80 9 123 -12 169 -12C221 -11 288 15 342 59C403 109 431 165 431 225C431 308 366 395 238 395C212 395 165 379 127 364L153 550Z"></path></g></svg></span></td></tr><tr><td class="align_left">KCNK6</td><td class="align_center">-0.05554</td><td class="align_center">0.945978</td><td class="align_center">0.899089</td><td class="align_center">0.995311</td><td class="align_center">0.032261</td></tr><tr><td class="align_left">MAL</td><td class="align_center">0.002416</td><td class="align_center">1.002419</td><td class="align_center">1.001031</td><td class="align_center">1.003809</td><td class="align_center">0.000632</td></tr><tr><td class="align_left">MUCL1</td><td class="align_center">0.002946</td><td class="align_center">1.002951</td><td class="align_center">1.001758</td><td class="align_center">1.004145</td><td class="align_center"><span style="width: 55.9003ptpx;"><svg height="8.98583pt" id="M23" style="vertical-align:-0.3499308pt" version="1.1" viewbox="-0.0498162 -8.6359 55.9003 8.98583" width="55.9003pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 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132 495 93 469 70C439 43 409 35 332 35C272 35 241 37 225 50C211 61 211 89 222 149L253 320H350C441 320 443 312 441 239H471L510 434H481C455 366 448 358 360 358H260L303 572C311 613 312 615 348 615H431C509 615 522 603 532 581C544 555 546 531 545 491L574 493C583 555 592 631 593 650Z"></path></g><g transform="matrix(.013,0,0,-0.013,32.598,0)"><path d="M535 230V280H52V230H535Z"></path></g><g transform="matrix(.013,0,0,-0.013,43.134,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,49.374,0)"><path d="M137 343C167 482 260 545 321 574C357 591 397 603 429 609L423 641C382 634 335 622 295 608C189 570 37 457 37 238C37 84 125 -12 242 -12C362 -12 447 89 447 209C447 311 374 393 267 393C247 393 226 386 204 376L137 343ZM227 337C318 337 361 256 361 173C361 105 336 22 258 22C176 22 126 120 126 240C126 266 127 291 132 310C155 323 189 337 227 337Z"></path></g></svg></span></td></tr><tr><td class="align_left">OR2W3</td><td class="align_center">0.290267</td><td class="align_center">1.336784</td><td class="align_center">1.132684</td><td class="align_center">1.577661</td><td class="align_center">0.000595</td></tr><tr><td class="align_left">RBP2</td><td class="align_center">0.047118</td><td class="align_center">1.048245</td><td class="align_center">0.998892</td><td class="align_center">1.100037</td><td class="align_center">0.055503</td></tr><tr><td class="align_left">STAC</td><td class="align_center">0.754457</td><td class="align_center">2.126455</td><td class="align_center">1.56286</td><td class="align_center">2.893294</td><td class="align_center"><span style="width: 55.9003ptpx;"><svg height="8.98583pt" id="M24" style="vertical-align:-0.3499308pt" version="1.1" viewbox="-0.0498162 -8.6359 55.9003 8.98583" width="55.9003pt" xmlns="http://www.w3.org/2000/svg" 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242 -12C362 -12 447 89 447 209C447 311 374 393 267 393C247 393 226 386 204 376L137 343ZM227 337C318 337 361 256 361 173C361 105 336 22 258 22C176 22 126 120 126 240C126 266 127 291 132 310C155 323 189 337 227 337Z"></path></g></svg></span></td></tr><tr><td class="align_left">ZNF829</td><td class="align_center">0.390186</td><td class="align_center">1.477256</td><td class="align_center">1.112411</td><td class="align_center">1.961761</td><td class="align_center">0.007017</td></tr><tr class="table-tr"><td colspan="6"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Regression coefficients of the nine <i>TP53</i> mutational status-associated prognostic genes.</div>

Oxidative Medicine and Cellular Longevity

tab2

Table 2

Table 2: Significance of <i>TP53</i> Mutational Status-Associated Signature in the Progression and Prognosis of Endometrial Carcinoma 

Oxidative Medicine and Cellular Longevity

Significance of TP53 Mutational Status-Associated Signature in the Progression and Prognosis of Endometrial Carcinoma

Table 2