HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis

<div>(a) HBO1 knockdown alleviated the pathological changes of the liver. (b) HBO1 expression was elevated by western blot in the CCL4-induced liver model. The protein samples were then subjected to SDS-PAGE and transferred to PVDF membranes. The immunoprotein bands were exposed using Bio-Rad fluorescence system. (c) Lentivirus was mainly enriched on liver tissue after injection. (d) HBO1 knockdown group could reduce liver damage in the mice by HE staining. (e) HBO1 knockdown group could reduce collagen deposition compared to the control group. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis 