Nur77 Deficiency Exacerbates Macrophage NLRP3 Inflammasome-Mediated Inflammation and Accelerates Atherosclerosis

Figure 1

Nur77 deficiency promotes atherosclerotic plaque progression and destabilization. (a) Schematic illustration of the study design of the timeline and treatment protocol. (b) Representative magnetic resonance images of the cross-sections of LCCA in mice from each group 4 weeks after the surgeries (scale  mm). The vascular lumen was shown by a white arrow. (c) Representative gross images of LCCA segments (scale  mm) and HE staining of LCCA sections in mice from each group (scale  μm). (d) Quantification of the carotid atherosclerotic plaque areas in mice from each group (). Values are shown as the . LCCA: left common carotid artery; LRA: left renal artery; L: left. .

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