Nur77 Deficiency Exacerbates Macrophage NLRP3 Inflammasome-Mediated Inflammation and Accelerates Atherosclerosis

Figure 3

Effect of Nur77 deficiency on macrophage inflammatory responses of atherosclerotic lesions. (a) Representative immunofluorescence staining of CD68 (red), c-caspase-1 (green), and their colocalization (yellow) of carotid atherosclerotic lesions in mice from each group (scale  μm). (b) Quantification of c-caspase-1+ CD68+ areas relative to the total CD68+ area (). (c) Representative immunofluorescence staining of CD68 (red), c-IL-1β (green), and their colocalization (yellow) of carotid atherosclerotic lesions in mice from each group (scale  μm). (d) Quantification of c-IL-1β+ CD68+ areas relative to the total CD68+ area (). Values are shown as the . .

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