Research Article
Pyrocatechol Alleviates Cisplatin-Induced Acute Kidney Injury by Inhibiting ROS Production
Figure 8
Pyrocatechol mitigated apoptosis in cisplatin-injured kidneys. (a) Expression of apoptosis-associated proteins B-cell lymphoma 2 (Bcl-2) and Cleaved Caspase-3 in pyrocatechol-treated kidney tissue lysates by Western blotting. (b) Representative images of TUNEL staining tests in kidney tissue. Scale bar, 100 μM. Quantification of the number of positive cells assessed for TUNEL staining. Data are presented as (). (c) Schematic diagram illustrating PCL inhibition of cisplatin-mediated apoptosis upregulating GPX4 to regulate AKI. The statistical analysis was performed with one-way ANOVA.
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