Aging-Related Endothelial Progenitor Cell Dysfunction and Its Association with IL-17 and IL-23 in HFmrEF Patients

Table 1

Clinical and biochemical characteristics of younger and older patients with HFmrEF.

Characteristics	Younger group ()	Older group ()
Age (years)	58.0 (47.0,60.5)	80.0 (70.5,84.0)^#
Male (, %)	23 (92.0%)	25 (75.8%)
Heart rate (time/min)	80.0 (76.0, 102.0)	80.0 (73.5, 93.0)
Systolic BP (mmHg)
Diastolic BP (mmHg)
BMI (kg/m^2)	20.6 (20.3, 23.9)	20.0 (18.7, 23.7)
Plasma glucose (mmol/L)	7.1 (5.8, 8.7)	7.9 (6.1, 9.5)
Cr (mmol/L)	109.0 (78.5, 225.0)	108.0 (75.5, 184.5)
TC (mmol/L)
TG (mmol/L)	1.2 (1.0, 2.0)	1.2 (0.8, 1.6)
HDL (mmol/L)	0.9 (0.7, 1.1)	1.0 (0.8, 1.4)
LDL (mmol/L)
NT pro-BNP (pg/mL)	1883.0 (435.3,30168.5)	4288.0 (817.0,23584.0)
Septal E’ (cm/s)	5.0 (4.0,6.5)	5.0 (3.5,6.0)
LVEDD (mm)
TAPSE (mm)
LVEF (%)	44.0 (42.0, 46.5)	43.0 (42.0, 45.0)
MAGGIC score	11.0 (8.5,20.0)	29.0 (23.5,32.5)^#

Abbreviations: BMI: Body mass index; BP: Blood pressure; Cr: Serum creatinine; TC: Total cholesterol; TG: Triglyceride; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; LVEDD: Left ventricular end-diastolic diameter; TAPSE: Tricuspid annulus systolic plane excursion; LVEF: Left ventricular ejection fraction; MAGGIC: Meta-analysis Global Group in Chronic Heart Failure. Notes: Normally distributed data are given as the mean ± SD and nonnormally distributed data as the median (25%, 75%). The differences between the groups with nonnormally distributed data were compared with the Mann–Whitney -test, while the Student’s -test was used for normally distributed data. ^#vs. younger group.