Research Article

Serum Lipopolysaccharide Is Associated with the Recurrence of Atrial Fibrillation after Radiofrequency Ablation by Increasing Systemic Inflammation and Atrial Fibrosis

Table 2

Multivariable Cox regression to predict RAF.

VariablesHazard ratio (95% CI)

Age (year)0.990 (0.954-1.027)0.598
Persistent AF, (%)1.018 (0.520-1.992)0.959
Hypertension, (%)1.117 (0.562-2.221)0.752
Diabetes, (%)1.505 (0.596-3.796)0.387
CHD, (%)0.794 (0.331-1.905)0.606
Heart failure, (%)2.029 (1.030-3.997)0.041
BMI (kg/m2)1.065 (0.972-1.167)0.178
LAD (mm)1.064 (1.009-1.123)0.022
Hs-CRP (mg/L)1.689 (0.456-6.253)0.433
IL-6 (pg/mL)1.009 (0.995-1.023)0.226
CITP (ng/mL)6.841 (1.168-40.069)0.033
TGF-β1 (ng/mL)1.021 (0.998-1.045)0.079
Log-LPS (pg/mL)5.686 (1.055-30.635)0.043

CHD: coronary heart disease; BMI: body mass index; LAD: left atrial diameter; IL-6: interleukin-6; CITP: collagen type-1 C-terminal telopeptide; TGF-β1: transforming growth factor beta1; LPS: lipopolysaccharide.