Theaflavin-3,3-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways

Figure 2

TFDG alleviates inflammatory responses in chondrocytes. (a–d) The transcription levels of iNOS, Ptgs2, TNF-α, and IL-6 were determined by RT-qPCR. (e–g) The protein expressions of iNOS and COX2 were analyzed by western blotting. The grey values normalized with β-actin and control group were quantified by ImageJ. (h–k) Proinflammatory cytokines such as PGE2, IL-1β, IL-6, and TNF-α from chondrocytes in different groups detected by ELISA. The bar graph shows the of data (). , , , and .

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