Research Article

Antioxidative Stress and Antiapoptosis Effect of Chitosan Nanoparticles to Protect Cardiac Cell Damage on Streptozotocin-Induced Diabetic Rat

Figure 5

Photomicrograph of immunohistochemical staining of Caspase-3 expression of rat heart tissue. (A) Caspase-3 expression in rat heart (black arrow) from the control group (a); streptozotocin group (b); and chitosan nanoparticles group at dose 75 mg/kg Bw (c), 150 mg kg/BW (d), and 300 mg/kg BW. B. IOD/μm2 shows Caspase-3 expression from semiquantitative evaluation (400×).
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