High Glucose Promotes Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance and Invasion through Modulating ROS/MMP-3 Signaling Pathway

Table 2

Baseline information of MMP-3 differently expressed groups (TCGA database).

Characteristic	MMP3(low)	MMP3(high)	value
Overall cases	89	89
T stage, (%)			0.290
T1	4 (2.3%)	3 (1.7%)
T2	16 (9.1%)	8 (4.5%)
T3	66 (37.5%)	76 (43.2%)
T4	1 (0.6%)	2 (1.1%)
stage, (%)			0.375
N0	28 (16.2%)	22 (12.7%)
N1	58 (33.5%)	65 (37.6%)
stage, (%)			0.672
M0	38 (45.2%)	41 (48.8%)
M1	3 (3.6%)	2 (2.4%)
Pathologic stage, (%)			1.000
I-II	83 (47.4%)	84 (48%)
III-IV	4 (2.3%)	4 (2.2%)
Sex (male)	53 (29.8%)	45 (25.3%)	0.292
Histologic grade, (%)			0.008
G1	23 (13.1%)	8 (4.5%)
G2	39 (22.2%)	56 (31.8%)
G3	25 (14.2%)	23 (13.1%)
G4	1 (0.6%)	1 (0.6%)
OS event, (%)			<0.001
Alive	55 (30.9%)	31 (17.4%)
Dead	34 (19.1%)	58 (32.6%)
Age	67 (58-73)	65 (57-73)	0.448