Research Article

[Retracted] Siglec-15 Regulates the Inflammatory Response and Polarization of Tumor-Associated Macrophages in Pancreatic Cancer by Inhibiting the cGAS-STING Signaling Pathway

Figure 3

The effect of Siglec-15 on the glycolytic pathway of RAW264.7 macrophages. (a) Bone marrow cells from wild-type and Siglec-15 knockout mice were extracted in vitro and induced into bone marrow-derived macrophages (BMDMs). The effect of IL-4 stimulation on ECAR of BMDMs cells. (B) The effect of IL-4 stimulation on the ECAR of BMDMs cells. (c) The effect of IL-4 stimulation on the lactic acid production of BMDMs cells. (d) The effect of IL-4 stimulation on HK enzyme activity. (e) The effect of Siglec-15 knockout of RAW264.7 and BMDMs on the transcription level of glycolysis-related genes.
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