Minocycline Alleviates White Matter Injury following Intracerebral Hemorrhage by Regulating CD4⁺ T Cell Differentiation via Notch1 Signaling Pathway

Figure 7

Minocycline activated the Notch1 signaling in CD4⁺ T cells after ICH. (a) Representative immunostaining images of CD4 and Notch1 in different groups. (b) CD4⁺ T cells were cultured in vitro with PBS, minocycline, hemoglobin + PBS, and hemoglobin + Mino to check the protein levels of Notch1 signal. (c) Quantification of protein levels of Notch1 signal in different groups. , vs. the T cell + OPCs group; ^#### vs. the T cell+ OPCs+ hemoglobin group.

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