[Retracted] miR-92b-3p Exerts Neuroprotective Effects on Ischemia/Reperfusion-Induced Cerebral Injury via Targeting NOX4 in a Rat Model

<div>NOX4 functioned as a direct target gene of miR-126a-5p. (a) Analysis of miR-92b-3p targets. (b) Analysis of NOX4 (TECPR2) target miRNA. (c) Sequence analysis of miR-92b-3p and NOX4. (d) The luciferase reporter vector of NOX4-WT or NOX4-MT was cotransfected with NC mimic or miR-92b-3p mimic in 293T cells. After 48 h transfection, the relative luciferase activity was evaluated. SH-SY5Y cells were treated with miR-126a-5p mimic or NC mimic for 48 h. (e) mRNA and (f) protein levels of NOX4 regulated by miR-126a-5p in SH-SY5Y cells measured by qRT-PCR and Western blot. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: [Retracted] miR-92b-3p Exerts Neuroprotective Effects on Ischemia/Reperfusion-Induced Cerebral Injury via Targeting NOX4 in a Rat Model 