The E3 Ubiquitin Ligase SYVN1 Plays an Antiapoptotic Role in Polycystic Ovary Syndrome by Regulating Mitochondrial Fission

Figure 3

Overexpression of SYVN1 inhibited mitochondrial fission in KGN cells. KGN cells were transfected with empty, SYVN1, control siRNA, or SYVN1 siRNA plasmids for 24 h. (a) Imaging of mitochondrial morphology in each group by confocal microscopy using MitoTracker Red.  μm. (b, c) Protein expression of Drp1 and Mfn1 in each group was detected by western blotting. The data are expressed as . . One-way ANOVA with Tukey’s multiple comparison test. (b) , . , ; (c) , . , .

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