Endothelial MicroRNA-483-3p Is Hypertension-Protective

Figure 2

The serum miR-483-3p level has a positive correlation with vascular function. Serum levels of (a) NO and (b) ET-1 (HTN₂, ; HC, ) measured by ELISA. (c) Flow-mediated dilation (FMD) and (d) brachial-ankle pulse wave velocity (baPWV) were measured for evaluations of endothelial function and vascular damage, respectively. (e–h) The qPCR analysis of miR-483-3p levels in sera collected from cohort 2. The correlation analysis between serum levels of miR-483-3p and those of (e) NO, (f) ET1, (g) FMD, and (h) baPWV was carried out using a nonlinear regression model. Data are shown as . Significance for data was performed by Student’s two-tailed test. .

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