Exploring the Resistance Mechanisms of Distal D835V Mutation in FLT3 to Inhibitors

Figure 10

(a) The binding pocket of sorafenib in 4RT7-WT and (b) the binding pocket of crenolanib in 6JQR-WT. The protein is shown in gray. Sorafenib is shown in yellow sticks, and crenolanib is shown in orange sticks.

(a)

(b)