Exploring the Resistance Mechanisms of Distal D835V Mutation in FLT3 to Inhibitors

Figure 4

DCCM from MD simulations. (a) 4RT7-WT+sorafenib; (b) 4RT7-D835V+sorafenib; (c) 6JQR-WT+crenolanib; and (d) 6JQR-D835V+crenolanib.