KCNH6 Enhanced Hepatic Glucose Metabolism through Mitochondrial Ca²⁺ Regulation and Oxidative Stress Inhibition

Figure 5

KCNH6 improved glucose metabolism through the JNK and p38^MAPK pathways. (a) Protein levels of JNK signaling pathway-related genes in HepG2 cells. (b) Protein levels of p38^MAPK signaling pathway-related genes in HepG2 cells. (c) Levels of JNK signaling pathway-related genes in WT and KO mice. (d) Protein expression levels of p38^MAPK signaling pathway-related genes in WT and KO mice. and vs. WT or Ctrl. ^# and ^## vs. Kcnh6 (, a–d). Statistical comparisons were calculated using the Mann–Whitney test.

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