In Vitro Synergistic Inhibitory Activity of Natural Alkaloid Berberine Combined with Azithromycin against Alginate Production by Pseudomonas aeruginosa PAO1

Table 2

Susceptibility of BER and AZM alone and in combination against planktonic PAO1.

Strain	MIC alone (μg/mL)		MIC in combination (μg/mL)		FICI (interpretation)
	BER	AZM	BER	AZM
PAO1	>1250	256	312.5	64	0.5

Note: PA: Pseudomonas aeruginosa; MIC: Minimum Inhibitory Concentration; BER: berberine; AZM: azithromycin; FICI: Fractional Inhibitory Concentration Index.