[Retracted] Taurine Ameliorates Iron Overload-Induced Hepatocyte Injury via the Bcl-2/VDAC1-Mediated Mitochondrial Apoptosis Pathway

Figure 5

Taurine protects mitochondrial membrane integrity. Taurine treatment blocks the opening of mPTP in L02 cells caused by iron overload injury. (a) CaCl₂ (200 μM) was added for 20 min, and absorbance was measured at a wavelength of to indicate the opening of mPTP. (b) Calculating the opening of mPTP as . Taurine treatment blocks the transfer of Cyt c from mitochondria to the cytoplasm. (c, d) Cyt c protein level in the cytoplasm and mitochondria. (e) Histogram of Cyt c expression level in the cytoplasm. (f) Histogram of Cyt c expression level in the mitochondria. Data values are expressed as the (SEM), . vs. the control group. ^## vs. the iron group. ^&& vs. the iron+taurine group. ^& vs. the iron+taurine group.

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