Aerobic Exercise with Mediterranean-DASH Intervention for Neurodegenerative Delay Diet Promotes Brain Cells’ Longevity despite Sex Hormone Deficiency in Postmenopausal Women: A Randomized Controlled Trial

Table 4

Multiple linear regression model showing the association among changes (post-pre) in sex hormones and cognitive functions and functional level, in both groups.

Variables	Experimental group				Control group
	RUDAS		FIM		RUDAS		FIM
		value		value		value		value
Estradiol (pg/ml)	0.139	0.479	0.492	0.363	.121	0.449	0.699	0.041
Total testosterone (ng/ml)	-10.056	0.253	-10.712	0.654	-7.095	0.603	18.995	0.501
Free testosterone (pg/ml)	1.085	0.205	-2.802	0.232	1.580	0.108	2.882	0.153
SHBG (nmol/ml)	0.046	0.734	0.168	0.650	0.173	0.458	0.868	0.079

Values are presented as beta coefficient and value of each parameter. value <0.05 is considered statistically significant according to multiple regression analysis. FIM: functional independence measure; RUDAS: Rowland Universal Dementia Assessment Scale; SHBG: sex hormone binding globulin.