[Retracted] <i>DNA Topoisomerase II-α</i> Regulated by miR-22-5p Promotes Hepatocellular Carcinoma Invasion and Migration through the Hippo Pathway

<div><i>TOP2A</i> overexpression promotes HCC <i>invasion and migration in vitro</i>. (a) TOP2A expression in SK-HEP-1 cells transfected with TOP2A was determined by RT-qPCR. (b) Western blot analysis of indicated HCC cells (SK-HEP-1) transfected with TOP2A-vector (Ctrl group) or TOP2A (TOP2A group). (c) Transwell invasion assay of HCC cells transfected with Ctrl or TOP2A. The bar graphs show the number of migrating and invasive cells after 24 h. (d) Representative images of wound healing assays after scratch wounding of the cells described. (e) Western blot analysis was performed to detect the epithelial mesenchymal protein expression in HCC cells transfected with Ctrl or TOP2A. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: [Retracted] <i>DNA Topoisomerase II-α</i> Regulated by miR-22-5p Promotes Hepatocellular Carcinoma Invasion and Migration through the Hippo Pathway 

Figure 4 | [Retracted] DNA Topoisomerase II-α Regulated by miR-22-5p Promotes Hepatocellular Carcinoma Invasion and Migration through the Hippo Pathway 