Investigating the Mechanisms of Jieduquyuziyin Prescription Improves Lupus Nephritis and Fibrosis via FXR in MRL/lpr Mice

Figure 6

NF-κB nuclear transfer decreased in the mouse kidney. The relationship between FXR and α-SMA regulation was investigated through in vitro experiments. WB results (a–c) demonstrated IκB phosphorylation and NF-κB nuclear transfer (). (d) Renal pathology of clinical lupus patients with FXR (red) and α-SMA (green) double staining (scale bar, 100 μm).

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