[Retracted] Knockdown of miR-372-3p Inhibits the Development of Diabetic Cardiomyopathy by Accelerating Angiogenesis via Activating the PI3K/AKT/mTOR/HIF-1α Signaling Pathway and Suppressing Oxidative Stress

Figure 4

Effect of miR-372-3p KD on the AKT/mTOR/HIF-1α signaling pathway. (a) Protein expressions of p-PI3K, PI3K, p-AKT, AKT, mTOR, p-mTOR, P70S6K, and p-P70S6K HIF-1α in the control, model, and miR-372-3p KD groups were identified by Western blotting. β-Actin was considered as a loading control. (b) Statistical analysis was performed to examine the expressions of p-PI3K, PI3K, p-AKT, AKT, mTOR, p-mTOR, P70S6K, p-P70S6K, and HIF-1α in myocardial tissues. (c) Protein expressions of NOX2 and NOX4 in the control, model, and miR-372-3p KD groups were identified by Western blotting. β-Actin was considered as a loading control. (d) Statistical analysis was performed to examine the expressions of NOX2 and NOX4 in myocardial tissues. Data were presented as , /group, and : model group vs. miR-372-3p KD group.

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