[Retracted] Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti-inflammatory Mechanism

Figure 4

Effects of carveol on LPS-induced neuronal apoptosis. (a) Immunohistochemistry results for Bcl-2 in the cortex and hippocampus. Scale bar 50 μm, magnification 40x. Data are expressed as . and are compared to the saline group; ## and # indicate a significant difference compared to the LPS group, while ^† is compared to ATRA+LPS. (b) Immunohistochemistry results for p-JNK in the cortex and hippocampus. Scale bar 50 μm, magnification 40x. Data are expressed as . and are compared to the saline group; ## and # indicate a significant difference compared to the LPS group; † is compared to ATRA+LPS. The immunohistochemistry sections were prepared after the euthanization of animals following behavioral analysis. The saline, LPS, CAR+LPS, and FLX + LPS groups were taken as the first cohort (/group), while the ATRA+LPS, CAR+ATRA+LPS, and ATRA+LPS + FLX groups were from the second cohort (/group). LPS: lipopolysaccharide; ATRA: all-trans retinoic acid; FLX: fluoxetine; p-JNK: Jun N-terminal kinase; Bcl-2: B cell lymphoma-2.