Research Article
Markers of Inflammation, Oxidative Stress, and Fibrosis in Patients with Atrial Fibrillation
Table 1
Demographic and clinical characteristics of AF patients and controls.
| | Variable | AF patients () | Controls () | value |
| | Age (years) | 58 (±9) | 57 (±11) | 0.545 | | Male, (%) | 54 (72.0) | 54 (72.0) | 1.000 | | Height (cm) | 175 (±10) | 175 (±10) | 0.949 | | Weight (kg) | 90.1 (±16.6) | 81.3 (±16.4) | 0.001 | | Body mass index (kg/m2) | 29.4 (±4.7) | 26.4 (±3.7) | <0.001 | | Heart rate (beats per minute) | 59 (±9) | 61 (±8) | 0.077 | | Peripheral systolic blood pressure (pSBP) (mmHg) | 127 (±13) | 128 (±15) | 0.557 | | Peripheral diastolic blood pressure (pDPB) (mmHg) | 79 (±9) | 78 (±8) | 0.861 | | Peripheral pulse pressure (pPP) (mmHg) | 48 (±9) | 50 (±11) | 0.375 | | hsCRP (mg/l) | 1.5 (0.9-3.8) | 1.1 (0.6-2.0) | 0.001 | | MPO (ng/l) | 52.6 (31.9-86.0) | 36.2 (20.9-54.9) | <0.001 | | Galectin-3 (mg/l) | 11.4 (9.6-14.5) | 9.7 (8.9-12.0) | 0.003 | | oxLDL (U/l) | 71.5 (60.5-94.3) | 71.7 (56.3-87.7) | 0.449 | | NT-proBNP (pg/ml) | 209.0 (99.5-827.0) | 28.0 (20.0-43.0) | <0.001 | | Ejection fraction (%) | 58 (±9) | 64 (±6) | 0.015 | | Left atrial diameter (cm) | 4.0 (±0.5) | 3.6 (±0.4) | 0.001 | | Left atrial end systolic volume index (ml/m2) | 36.3 (±9.7) | 23.3 (±4.5) | <0.001 |
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Values are presented as or median (IQR) or count (%). SD: standard deviation; IQR: interquartile range; hsCRP: high-sensitivity C-reactive protein; MPO: myeloperoxidase; oxLDL: oxidized low-density lipoprotein; NT-proBNP: N-terminal pro-brain natriuretic peptide. |
