Markers of Inflammation, Oxidative Stress, and Fibrosis in Patients with Atrial Fibrillation
Table 3
Demographic and clinical characteristics of AF patients with successful and unsuccessful maintenance of sinus rhythm after follow-up of one year and healthy controls.
Variable
Unsuccessful AF patients ()
Successful AF patients ()
Controls ()
value (unsuccessful vs. successful)
value (successful vs. controls)
Age (years)
59 (±10)
57 (±9)
57 (±11)
0.536
0.739
Male (%)
24 (80.0)
30 (66.3)
52 (71.2)
0.319
0.751
Height (cm)
175 (±11)
175 (±10)
175 (±10)
0.911
0.846
Weight (kg)
94.0 (±20.0)
87.6 (±13.6)
80.7 (±16.1)
0.102
0.018
Body mass index (kg/m2)
30.7 (±5.7)
28.6 (±3.6)
26.3 (±3.7)
0.055
0.001
Heart rate (beats per minute)
63 (±10)
56 (±8)
61 (±8)
0.002
0.001
Peripheral systolic blood pressure (pSBP) (mmHg)
124 (±14)
128 (±12)
128 (±16)
0.168
0.945
Peripheral diastolic blood pressure (pDPB) (mmHg)
78 (±8)
78 (±9)
78 (±8)
0.961
0.817
Peripheral pulse pressure (pPP) (mmHg)
46 (±8)
50 (±9)
50 (±11)
0.036
0.985
hsCRP (mg/l)
1.9 (1.0-4.4)
1.5 (1.2-3.1)
1.1 (0.6-2.0)
0.859
0.004
MPO (ng/l)
84.3 (42.9-132.5)
40.5 (31.0-71.7)
35.1 (20.8-55.4)
0.005
0.052
Galectin-3 (mg/l)
11.8 (10.9-14.4)
10.8 (9.3-14.5)
9.7 (8.9-12.0)
0.355
0.024
oxLDL (U/l)
67.2 (60.1-80.2)
75.7 (64.0-101.1)
71.7 (57.0-87.0)
0.107
0.165
NT-proBNP (pg/ml)
694.0 (241.0-1170.0)
127.5 (83.8-237.0)
28.0 (20.0-43.0)
<0.001
<0.001
Ejection fraction (%)
54 (±10)
61 (±8)
64 (±6)
<0.001
0.154
Left atrial diameter (cm)
4.0 (±0.5)
4.0 (±0.5)
3.6 (±0.4)
0.983
0.002
Left atrial end systolic volume index (ml/m2)
36.0 (±11.5)
36.6 (±8.4)
23.3 (±4.5)
0.797
<0.001
Values are presented as or median (IQR) or count (%). SD: standard deviation; IQR: interquartile range; hsCRP: high-sensitivity C-reactive protein; MPO: myeloperoxidase; oxLDL: oxidized low-density lipoprotein; NT-proBNP: N-terminal pro-brain natriuretic peptide.
