Investigating Causal Relations between Genetic-Related Intermediate Endophenotype and Risk of Chronic Prostatitis: Mendelian Randomization Study

Table 1

Clinical biochemical indicator shared SNP sites with chronic prostatitis.

Exposure (indicators)	Outcome (CP) number of shared SNP	Exposure (indicators)	Outcome (CP) number of shared SNP	Exposure (indicators)	Outcome (CP) number of shared SNP
Complement C4	286	FSH	2	IgA	0
FOL	20	IgM	1	BUN	0
CRP	15	LDL	1	IgE	0
HCY	15	FERR	1	Insulin	0
Estradiol	15	SHBG	1	ALT	0
Uric acid	4	TG	0	TE	0
Complement C3	3	Cholesterol	0	Creatinine	0
B12	2	BMI	0	Glucose	0
HDL	2	ASO	0	Triglyceride	0
AFP	2	IgG	0

Note: CP: chronic prostatitis; FOL: folic acid; CRP: C-type reactive protein; HCY: homocysteine; B12: vitamin B12; HDL: high-density lipoprotein; AFP: alpha-fetoprotein; FSH: follicle-stimulating hormone; LDL: low-density lipoprotein; FERR: ferritin; SHBG: sex hormone-binding globulin; TG: triglyceride; BMI: body mass index; ASO: antistreptolysin O; IgG: immunoglobulin G; IgA: immunoglobulin A; IgE: immunoglobulin E; BUN: blood urea nitrogen; ALT: alanine transaminase; SNP: single-nucleotide polymorphism.