Paeoniflorin Upregulates Mitochondrial Thioredoxin of Schwann Cells to Improve Diabetic Peripheral Neuropathy Indicated by 4D Label-Free Quantitative Proteomics

Figure 1

Identification of targeted protein Trx2 via 4D Label-free quantification. (a) The strategy for 4D Label-free quantification of the proteome of mitochondria in Schwann cells. (b) Histogram of the number distribution of differentially expressed proteins in different comparison groups. (c) Volcano plot of differentially expressed proteins. The red box indicates that it is related to Trx2. (d) Subcellular localization chart of differentially expressed proteins in mitochondria (HG_PF/HG). (e) Statistical distribution chart of upregulated proteins under each GO category (2nd level) (HG_PF/HG).

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