Paeoniflorin Upregulates Mitochondrial Thioredoxin of Schwann Cells to Improve Diabetic Peripheral Neuropathy Indicated by 4D Label-Free Quantitative Proteomics

Table 1

Mitochondrial localization of differentially expressed proteins by PF.

Protein accession	Protein description	HG_PF/HG ratio	Regulated type	HG_PF/HG value	Gene name
P97615	Thioredoxin, mitochondrial	3.112	Up	0.005	Txn2 (Trx2)
Q5BJT6	Large subunit GTPase 1 homolog	4.244	Up	0.031	Lsg1
Q5M818	39S ribosomal protein L16, mitochondrial	2.969	Up	0.005	Mrpl16
P61751	ADP-ribosylation factor 4	2.098	Up	0.022	Arf4
Q5RK08	Glioblastoma amplified sequence	2.031	Up	0.045	Nipsnap2
Q3B8R7	Mitochondrial ribosomal protein L47	1.938	Up	0.037	Mrpl47
D3ZIN7	Mitochondrial ribosomal protein	1.726	Up	0.050	Mrps23
Q5M7W7	Probable proline--tRNA ligase, mitochondrial	1.647	Up	0.020	Pars2
Q6P9Y4	ADP/ATP translocase 1	1.580	Up	0.0004	Slc25a4
B2RZD1	Protein transport protein Sec61 subunit beta	1.570	Up	0.030	Sec61b
D3ZU04	Uncharacterized protein	1.562	Up	0.023	—
P26772	10 kDa heat shock protein, mitochondrial	1.548	Up	0.006	Hspe1
G3V8Z3	G patch domain and KOW motifs	1.539	Up	0.033	Gpkow
D3ZF13	Acyl carrier protein	1.523	Up	0.002	Ndufab1
B0BN72	Mapk-regulated corepressor-interacting protein 1	1.513	Up	0.048	Mcrip1
D3ZYL4	Mitochondrial ribosomal protein L50	1.506	Up	0.020	Mrpl50
A0A0G2K9E5	Leucyl-tRNA synthetase 2, mitochondrial	0.603	Down	0.0002	Lars2
A0A0G2K1W9	Lactate dehydrogenase D	0.380	Down	0.041	Ldhd