Silencing TUFM Inhibits Development of Monocrotaline-Induced Pulmonary Hypertension by Regulating Mitochondrial Autophagy via AMPK/mTOR Signal Pathway

Figure 3

Expressions of TUFM and the autophagy indicators in different treated groups. (a) Western blot of TUFM, LC3II/I, Bax, Bcl2, BECN1, P62, and Apaf expression in each group as indicated. (b–h) Densitometry data represent the intensity of each group. Ctrl: normal control; PAH: pulmonary arterial hypertension; OE-NC: overexpression negative control; OE: overexpression of TUFM; Sh-NC: Sh-TUFM negative control; Sh: Sh-TUFM group. Data is presented as . each group. vs. Ctrl group, , , and ; ^# vs. PAH group, ^##, ^###, and ^####.

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