Suppressive Effect of Tetrahydrocurcumin on Pseudomonas aeruginosa Lipopolysaccharide-Induced Inflammation by Suppressing JAK/STAT and Nrf2/HO-1 Pathways in Microglial Cells

Figure 1

THC treatment exerts no significant effect on cell viability of BV2 microglial cells with or without P. a. LPS stimulation. (a) BV2 microglial cells were untreated (the mock group) or pretreated with THC (6.25, 12.5, 25, or 50 μM) for 24 h. (b) BV2 microglial cells were untreated (the mock group) or pretreated with THC (10, 20, or 40 μM) for 1.5 h following stimulation with P. a. LPS (0.1 μg/ml) for 24 h. CCK analysis indicated cell viability. The experimental quantitative data are presented in terms of the (). The treatment and mock group significantly differed. Bars with the same letter indicate no significant difference between the groups.

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