The lncRNA SEMA3B-AS1/HMGB1/FBXW7 Axis Mediates the Peritoneal Metastasis of Gastric Cancer by Regulating BGN Protein Ubiquitination

Table 1

The correlation of SEMA3B-AS1 expression with the clinicopathological parameters of GC patients ().

Parameters	(%)	SEMA3B-AS1 expression		value
		Low	High
Gender
Male	34 (68)	25	9	0.726
Female	16 (32)	11	5
Age
≥60 years	34 (68)	24	10	0.746
<60 years	16 (32)	12	4
Cancer grade
Moderate/well	10 (20)	6	4	0.345
Poor	40 (80)	30	10
Cancer size (cm)
≥5	13 (26.0)	13	0	0.009
<5	37 (74.0)	23	14
T stage
T1-2	11 (22.0)	4	7	0.003
T3-4	39 (78.0)	32	7
Lymphatic metastasis
N0-1	23 (46.0)	13	10	0.024
N2-3	27 (54.0)	23	4
Distant metastasis
Yes	11 (22.0)	11	0	0.019
No	39 (88.0)	25	14
TNM stage
I/II	17 (34.0)	7	10	<0.001
III/IV	33 (66.0)	29	4
CEA (ng/mL)
≥5	9 (18.0)	6	3	0.694
<5	41 (82.0)	30	11
CA19-9 (u/mL)
<37	40 (80.0)	28	12	0.529
≥37	10 (20.0)	8	2
PM
Yes	19 (38.0)	18	1	0.005
No	31 (62.0)	18	13

Remark: tumor staging guidelines: AJCC Cancer Staging Manual (8th). Abbreviations: TNM: tumor-node-metastasis; CEA: carcinoembryonic antigen; CA19-9: carbohydrate antigen 19-9; T stage: tumor invasion stage; PM: peritoneal metastasis. : statistically significant.