Postmenopausal Women with Breast, Endometrial, and Ovarian Cancers Have an Increased Risk for Cardiovascular Conditions prior to Active Endocrine Therapy
Table 5
Cardiovascular risk factors in BC, EC, and OC.
Cancer sites
CVRFs
SE
Wald
OR
95% CI
BC
Age
0.066
0.003
477.176
1.068
1.061-1.074
<0.001
μmol/L
0.481
0.087
30.709
1.618
1.365-1.918
<0.001
TG
0.095
0.025
13.960
1.100
1.046-1.156
<0.001
DM
2.211
0.098
512.460
9.124
7.535-11.049
<0.001
EC
Age
0.035
0.006
32.226
1.036
1.023-1.040
<0.001
μmol/L
0.722
0.160
20.407
2.059
1.505-2.816
<0.001
HDL-C
-0.515
0.261
3.908
0.597
0.358-0.996
0.048
TC
0.146
0.078
3.510
1.158
0.993-1.349
0.061
DM
2.201
0.183
144.206
9.037
6.309-12.944
<0.001
OC
Age
0.056
0.006
81.044
1.058
1.045-1.071
<0.001
μmol/L
0.646
0.172
14.153
1.907
1.362-2.670
<0.001
TG
0.130
0.069
3.537
1.139
0.995-1.304
0.060
DM
1.692
0.212
63.829
5.431
3.586-8.225
<0.001
BC: breast cancer; CI: confidence interval; CVRFs: cardiovascular risk factors; DM: diabetes mellitus; EC: endometrial cancer; HDL-C: high-density lipoprotein cholesterol; OC: ovarian cancer; OR: odds ratio; SE: standard error; SUA: serum uric acid; TC: total cholesterol; TG: triglycerides. Adjusted for age, SBP, μmol/L, TC, TG, HDL-C, and DM.
