[Retracted] Breast Cancer Exosome-Derived miR-425-5p Induces Cancer-Associated Fibroblast-Like Properties in Human Mammary Fibroblasts by TGFβ1/ROS Signaling Pathway

<div>Exosomes derived from MDA-MB-231 and BT549 cells promoted the transition of HMFs to the CAF phenotype. (a) Exosome identification by TEM. (b) Size distribution of MDA-MB-231- and BT549-derived exosome diameters. (c) Detection of TSG101 and HSP70 protein expression by western blot. (d) Human mammary fibroblasts. (e) Exosome uptake assay observed HMFs taking in MDA-MB-231- and BT549-derived exosomes. (f) Immunofluorescence staining observed the expression of α-SMA and FAPα in HMFs uptaking MDA-MB-231 and BT549 cell-derived exosomes.</div>

Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: [Retracted] Breast Cancer Exosome-Derived miR-425-5p Induces Cancer-Associated Fibroblast-Like Properties in Human Mammary Fibroblasts by TGFβ1/ROS Signaling Pathway

Figure 1 | [Retracted] Breast Cancer Exosome-Derived miR-425-5p Induces Cancer-Associated Fibroblast-Like Properties in Human Mammary Fibroblasts by TGFβ1/ROS Signaling Pathway 