The Effect of Enalapril, Losartan, or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

Table 3

Oxidative stress markers.

	Not antihypertensive -13			Enalapril -13			Losartan -13
	Baseline	One year	WCX	Baseline	One year	WCX	Baseline	One year
Oxidants
LPO (mM)			<0.01			0.1
NO (μg/mL)			0.8			0.3
Oxidative damage to DNA
8-OHdG (ng/mL)	^a		<0.01			0.02
Antioxidants
SOD (U/L)			<0.01			<0.01
GPx (nmol/min/mL)			0.03			0.9
TAC (μM)			<0.01		^b	<0.01

The results are expressed as . ^avs. Enalapril. ^bvs. Losartan. Wilcoxon rank test. Kruskal-Wallis test. ^a,bThe different letter denotes statistical significant difference using the Dunn-Bonferroni paired test. LPO: lipoperoxides; NO: nitric oxide; 8-OHdG: 8-hydroxy2-deoxyguanosine; SOD: superoxide dismutase; GPx: glutathione peroxidase. TAC: total antioxidant capacity.